Figure 8.
FIGURE 8. Mechanistic proposals for CDO. Scheme A,
mechanistic proposal for the catalytic cycle of cysteine
oxidation. The letter B in this Scheme A indicates a putative
active site base. Scheme B, mechanistic proposal for the single
turnover event generating the cysteinyl-tyrosine thioether
cross-link. Each mechanism is discussed in the text (see
"Discussion").
The above figure is reprinted
by permission from the ASBMB:
J Biol Chem
(2006,
281,
18723-18733)
copyright 2006.
