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Figure 8.
FIG. 8. Structures of Ecm1 and the active site. A, stereo
view of the structure of Ecm1 in complex with aza-AdoMet. B, a
2.2-Å simulated annealing omit map is shown contoured at
1.0  covering the aza-AdoMet
ligand. C, stereo view of the Ecm1 structure (Protein Data Bank
accession code 1RI2 [PDB]
) in complex with the GTP portion of the m7GpppG cap analog.
Potential hydrogen-bonding interactions are shown by dashed
lines; waters are rendered as red spheres. Amino acid residues
are labeled and shown in stick representation. aza-AdoMet and
GTP are shown in stick representation. The figure was generated
with Pymol software (W. L. DeLano, www.pymol.org).
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