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Figure 8.
Figure 8. An Overview of the Interacting Monomers in the
FabG·NADP^+ Complex
Glu168′ and its hydrogen
bonding interactions, as depicted in Figure 5B, are shown at the
interface. Shown in monomer A are the bound cofactor, the active
site residues, the ordered β5-α5 loop (purple), and Asn145,
which we propose may interact with the incoming pantetheine
moiety of the ACP-bound substrate. Shown in monomer B are
Arg129′ and Arg172′, which interact with the incoming ACP
(Zhang et al., 2003b). The figure was produced using MOLSCRIPT
(Kraulis, 1991) and rendered with RASTER3D (Merritt and Murphy,
1994).
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