Figure 8 - full size

 

Figure 8.
Figure 8. (a) Overlay of the 15 lowest energy structures of the PEMV-1 pseudoknot with loop 2 (green) and U[14] (purple) highlighted. (b) Details of the A[25], A[26], and A[27] non-canonical base-pairings between loop 2 (green) and stem 1 (blue) nucleotides. A[25] forms an N1-2' OH hydrogen bond with the sugar of C[16], A[27] forms the analogous interaction with the sugar of C[15], and A[26] forms a pair of reciprocal hydrogen bonds with G[8] from stem 1 (A[26] amino to G[8] N3, G[8] amino to A[26] N1, shown with donors in red, acceptors in blue).

The above figure is reprinted by permission from Elsevier: J Mol Biol (2002, 322, 621-633) copyright 2002.