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Figure 8.
Figure 8. Stacking of adjacent arginine-guanine pairing
alignments. (a) Intermolecular interactions between the
guanidinium groups of arginines 5, 7 and 13 and the major groove
edges of adjacent stacked G8, G24 and G25 residues in a
representative refined structure of the Rex peptide-RNA aptamer
complex. The G o C-rich stem II segment of the bound RNA is
shown in magenta in a space-filling representation with the
backbone phosphorus atoms in red. The peptide backbone in yellow
is shown in stick representation, whereas the three arginine
sidechains in yellow are shown in space-filling representation.
The intermolecular arginine-guanine pairing alignments involve
(b) R13 with G25, (c) R7 with G24 and (d) R5 with G8. Note that
we observe three distinct arginine-guanine pairing alignments in
the complex. This figure was prepared using INSIGHT II.
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