|
Figure 7.
Figure 7. Comparison between the structure adopted by peptide(P36-P46) in the complex with Fab F11.2.32 and the
conformation adopted by this segment in the native protease (PDB entry code 3hvp). (a) A schematic view of the pro-
tease in which the location of the epitope recognised by F11.2.32 is shown in red. (b) Ramachandran graph indicating
the differences in f-j angles of the segment 36 to 46 in the bound peptide (black) and the protease (red); residues are
named at the positions for the bound peptide and broken lines connect equivalent residues of the peptide and the
protease. Comparison of residues 36 to 45 of the protease (red) and bound peptide (yellow): (c) after superimposing
residues 36 to 40 and (d) after superimposing residues 41 to 44. The Figure was prepared with program MOLSCRIPT
(Kraulis, 1991).
|
