Figure 9 - full size

 

Figure 9.
Figure 9. Corey-Pauling-Koltum views of the d(A3-C4-[MC]G5-T6) · d(A13-C14-G15-T16) segment of the representative relaxation matrix refined structure (RM-B1 ) of the MC-DNA 9-mer complex. The mitomycin is shown in cyan, the DNA is shown in white except for the phosphates which are shown in red. A, View looking into minor groove and normal to the helix axis. B, An alternate view normal to the helix axis emphasizing the approximately parallel alignment of the MC ring and the sugar-phosphate backbone of the unmodified strand. C, View looking down the minor groove showing the MC ring directed towards the unmodified strand.

The above figure is reprinted by permission from Elsevier: J Mol Biol (1995, 247, 338-359) copyright 1995.