Figure 7 - full size

 

Figure 7.
Figure 7 Molecular surfaces of (a) apo-form PhoMPGP open conformation, (b) apo-form PhoMPGP closed conformation and (c) holo-form PhoMPGP. The sequestered surface in (c) is indicated in dark grey in (a) and (b). (d) Ribbon model of holo-form PhoMPGP viewed from the same angle as in (c). In (d), the phosphate and magnesium ions are indicated by a stick model and as a sphere, respectively. The mesh indicates the cavity detected by the program VOIDOO (Kleywegt & Jones, 1994[Kleywegt, G. J. & Jones, T. A. (1994). Acta Cryst. D50, 178-185.]) with a probe 1.4 Å in radius. The cavity had an ovoid-like shape with one protrusion where the phosphate ion binds in the active site.

The above figure is reprinted by permission from the IUCr: Acta Crystallogr D Biol Crystallogr (2008, 64, 1267-1276) copyright 2008.