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Figure 7.
Fig. 7. Structure of the HIV-2 myr(+)MA/di-C[4]-PI(4,5)P[2]
complex. (a,b) Interactions between di-C[4]-PI(4,5)P[2] (sticks)
and MA (colored according to electrostatic surface potential)
showing the 2′-fatty acid inserting in a preexisting cleft and
the inositol ring packing against a basic patch of the protein.
(c) PI(4,5)P[2] binding to the β-II–V cleft. (d) A network of
interactions implicated in PI(4,5)P[2] binding.
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