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Figure 7.
Figure 7. Model for the mechanism of Rv1264 regulation,
illustrated on the active (green) and inhibited states (blue) of
the holoenzyme, shown in surface representation. The two
structural features that accompany enzyme regulation are the
extension of α10 by the αN10-switch region and the different
placement of the fatty acid molecule, accompanied by a movement
of helix α4. Figure 7. Model for the mechanism of Rv1264
regulation, illustrated on the active (green) and inhibited
states (blue) of the holoenzyme, shown in surface
representation. The two structural features that accompany
enzyme regulation are the extension of α10 by the αN10-switch
region and the different placement of the fatty acid molecule,
accompanied by a movement of helix α4.
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