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Figure 7.
Figure 7. A sequence-dependent intramolecular switch
determines the cis/trans isomerization of metal-free legume
lectins. (a) Stereo view of the carbohydrate binding sites and
the C-terminal β-strands of apo-PAL (coloured according to atom
type), apo-GS-IB4^15 (red) and apo-con A^11 (yellow)
superimposed on each other. The hydrogen bonds between Asp208
and Asn104 in apo-con A are indicated by broken lines. (b)
Stereo view of an equivalent superposition for apo-PAL (coloured
according to atom type), ERGIC 53^38 (blue), Arcelin-1^36 (light
green) and Arcelin-5^35 (dark green).
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