Figure 7 - full size

 

Figure 7.
Figure 7. (A) An FoKFc omit electron density map of the substrate DXP in the active site of DXR, contoured at 3s. The position of the hydroxyl group in the L-configuration at C4 is depicted in green. (B) Hydrogen bonding interactions of the substrate DXP in the active site of DXR. The position of the hydroxyl group in the L-configuration at C4 is depicted in green. (C) A schematic diagram of the substrate DXP binding to DXR. For clarity, the bond between the carboxylate of E231 and the hydroxyl group of C4 of DXP has been omitted.

The above figure is reprinted by permission from Elsevier: J Mol Biol (2005, 345, 115-127) copyright 2005.