Figure 7 - full size

 

Figure 7.
FIG. 7. Schematic diagrams of the two possible hydrogen bonding schemes of the water channel near the purine N-1 position. A, hydrogen bonding scheme in which the first water molecule is a donor to N-1 of 6-aminopurines (distances are from the F-Ado A subunit). B, hydrogen bonding scheme in which the first water molecule is an acceptor from N-1 of 6-oxopurines (distances are from the Ino C subunit).

The above figure is reprinted by permission from the ASBMB: J Biol Chem (2003, 278, 47110-47118) copyright 2003.