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Figure 8.
Fig. 8. Electrondensitysurroundingresidues112-1 18 of the K116Nvariant.Shownisthe F, - F SA-omit mapcalculatedusing
thenucleaseAstructureexcluding the atoms of residues112-1 18. Mapis contouredat 1.5~. Densityyieldsthe conformation
of esidues112-114and116-1 17, ut conformation of residue115isnotclear. Two odels areshownwiththe map. A model
similar to hat of K116Dwasbiltandrefined to the data. B Amodelbased on he conformation found in the K116Gvariant
is also consistentwiththeelectron density. Although thedensity in the SA-omitmap favors the conformation of 115in
the K116G model (B), stericconsiderationssuggestthattheK116D (A) is morelikely to be adopted by K116N.
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