Figure 6 - full size

 

Figure 6.
Figure 6. Interaction between the Inter-SH2 Linker and the Kinase Domain
Detailed view showing the docking of Pro147 in the inter-SH2 linker into the cleft formed by the side chains of Tyr597 and Tyr598. Helix αI is shown as a light brown surface, and Tyr597 and Tyr598 are shown in magenta surface representation.

The above figure is reprinted by permission from Cell Press: Cell (2007, 129, 735-746) copyright 2007.