Figure 6 - full size

 

Figure 6.
FIGURE 6. Two-dimensional schematic representation of the protein-ligand contacts in the closed, pyruvate-bound structure (a) and the wrong-ligand crystallographic refinement model containing salicylate and pyruvate (b). The amino acid side chains are shown as sticks and labeled with the three-letter amino acid code, amino acid number, and monomer name. The pyruvate and salicylate molecules are depicted as ball-and-stick and are labeled "Pyr 1," "Pyr 2," and "SalI" with a monomer name of (E). The carbon atoms are black, and the oxygen atoms are white. This figure was generated with LIGPLOT (31).

The above figure is reprinted by permission from the ASBMB: J Biol Chem (2006, 281, 33441-33449) copyright 2006.