Figure 6 - full size

 

Figure 6.
Figure 6. (a) Putative active site region of E. coli PPX located at the interface of domains I and II. The pertinent residues are shown in stick representation. Surface representation of the interface between domains I and II in (b) E. coli PPX (closed state) and (c) A. aeolicus PPX/GPPA (open state). Both molecules are shown in the same orientation and were first superposed as in Figure 3. Domain colors are as in Figure 1, with highly conserved residues shown in yellow.

The above figure is reprinted by permission from Elsevier: J Mol Biol (2006, 359, 1249-1260) copyright 2006.