Figure 6 - full size

 

Figure 6.
Figure 6. Comparison of the bPIX-SH3/PAK2 structure to other bPIX-SH3 structures. (a) Superposition of the crystal and NMR structures of the bPIX-SH3/PAK complex. Peptides are illustrated in stick representation. The bPIX-SH3 surface is shown in gray, and the peptides are colored according to the legend in (a). (b) Structure of the bPIX-SH3/Cbl-b complex shown in ribbon representation (PDB code 2AK5). The two bPIX-SH3 domains and the Cbl-b peptide are colored according to the legend in (b). (c) Superposition of the bPIX-SH3/PAK2 crystal structure with the bPIX-SH3 B/Cbl-b crystal structure. bPIX-SH3 A has been removed for clarity. Peptides are illustrated in stick representation. The peptides of the crystal structures are colored according to the legend in (c).

The above figure is reprinted by permission from Elsevier: J Mol Biol (2006, 358, 509-522) copyright 2006.