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Figure 6.
Figure 6. Refinement model of the ALR2 binding pocket at
0.95 Å resolution occupied by the pyridazinone inhibitor 6
shown in blue. For clarity, the specificity pocket is
represented only in the open conformation. Amino acid residues
are shown in orange, water molecules are indicated as red
spheres. F[o] -F[c] density contoured at 3.5 s is shown in blue.
It clearly depicts the positions of the inhibitor atoms.
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