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Figure 6.
Packing of mAng-PO[4] crystals. (a) Transverse section through a solvent channel. (b)
Details of the interactions between the C-terminus and symmetry-related neighbours SYM MOL
1 and SYM MOL 2 (see text for details). Shown are mAng (residues 2-114 in red, residues
115-119 in gold), a superposed pdUppA-3'-p molecule obtained by alignment of the
mAng-PO[4]monomer with the RNase A-pdUppA-3'-p complex (PDB code 1qhc ; Leonidas,
Shapiro, Irons et al., 1999 [Leonidas, D. D., Shapiro, R., Irons, L. I., Russo, N. &
Acharya, K. R. (1999). Biochemistry, 32, 10287-10297.]-[bluearr.gif] ; blue) and
selected symmetry-related neighbours (grey/black). The side chains of Lys19, Arg24 and
Arg28 are disordered beyond C^ [beta] .
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