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Figure 6.
Figure 6. (A) An FoKFc omit electron density map of fosmidomycin in the active site of DXR, contoured at 3s. Met276
is shown in orange on the left and Met214 is shown in two conformations: that of SeMet214 in magenta (right) and that of
wild-type Met214 in orange (left). (B) Hydrogen bonding interactions of the inhibitor fosmidomycin in the active site of
DXR. (C) A schematic diagram of fosmidomycin binding to SeMet-labelled DXR.
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