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Figure 6.
Figure 6. Kinetic Model of GlucokinaseGlucokinase appears
to exist in three conformations and to have two catalytic
cycles. The ratio of two catalytic cycles is responsible for the
sigmoidal response to glucose. Although ordered process in the
slow cycle of glucokinase was indicated by isotope-exchange
experiment, the addition of substrates in the fast cycle may be
random.
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