Figure 6 - full size

 

Figure 6.
FIG. 6. Comparison of the oxidized and reduced forms of MDH-GOX2 at the enzyme active site. The side chains of Tyr26, Tyr131, backbone of Gly81, the flavin ring, the sulfate anion, and 7 waters of the oxidized protein are shown in atom colors (carbon yellow, oxygen red, nitrogen light blue, and sulfur green). Those atoms of Tyr26 and the 6 waters that show significant movement, as well as of the sulfate anion in the reduced enzyme, are shown in dark blue. This diagram was made using TURBO-FRODO (21).

The above figure is reprinted by permission from the ASBMB: J Biol Chem (2004, 279, 3749-3757) copyright 2004.