Figure 6.
Figure 6. The Catalytic Mechanism of Carnitine
AcyltransferasesThe catalytic His343 residue can extract the
proton from either carnitine or CoA. The oxyanion in the
tetrahedral intermediate is stabilized by interactions with
carnitine and the side chain hydroxyl of Ser554.
The above figure is reprinted
by permission from Cell Press:
Cell
(2003,
112,
113-122)
copyright 2003.
