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Figure 6.
Fig. 6. Putative structure of active GzmK bound to a
substrate/inhibitor. The crystal structure of pro-GzmK (blue) is
shown superimposed with a model of active GzmK (red). In
addition, the reactive site loop of the second Kunitz-type
domain of bikunin (1BIK, residues Gly89-Phe^94, yellow) has been
modeled into the active site region using the known complex
between BPTI and trypsin as a template. The figure was prepared
with WEBLABVIEWER (available at www.msi.com).
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