Figure 6.
Figure 6 (A) Deduced nucleic acid (brown) and protein (green)
interaction sites mapped onto the aaeNusG surface. The left
panel is in the same orientation as Figure 2C. The three domains
are labeled. Numbers identify potential interactions sites. 1,
S6-like nucleic acid interaction site; 2, U1A-like nucleic acid
interaction site; 3, nucleic acid interaction site mapped by
L24−rRNA contacts; 4, S18-like protein interaction site; 5,
tudor-like protein interaction site. If helix 3
of the RNP motif was removed upon U1A-like nucleic acid
interaction, additional contact sites would become uncovered.
Interaction sites that could not be deduced from the structures
may also exist in domain II. (B) Stereo-ribbon plot of aaeNusG
with the mutated residues in magenta (with phenotype) and light
blue (no phenotype).
The above figure is reprinted
from an Open Access publication published by Macmillan Publishers Ltd:
EMBO J
(2002,
21,
4641-4653)
copyright 2002.
3
of the RNP motif was removed upon U1A-like nucleic acid
interaction, additional contact sites would become uncovered.
Interaction sites that could not be deduced from the structures
may also exist in domain II. (B) Stereo-ribbon plot of aaeNusG
with the mutated residues in magenta (with phenotype) and light
blue (no phenotype).