Figure 6 - full size

 

Figure 6.
Figure 6 Stereoviews of symmetrically related pairs of allosteric effectors bound in the Hb central water cavity. Protein residues are shown as light blue sticks. RSR4 is blue, RSR13 is orange, TB5-27 is yellow and TB5-39 is red. Secondary-site binding for RSR4 is inter-dimer, while an intra-dimer binding mode is adopted by the TB5 compounds.

The above figure is reprinted by permission from the IUCr: Acta Crystallogr D Biol Crystallogr (2002, 58, 634-644) copyright 2002.