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Figure 6.
Figure 6. Substrate modeling by superposition on the
hapten. Most of the antibody interactions with the hapten and
substrate alike are directed towards the two phenyl rings. The
putative hydroxide ion is positioned to abstract the hydrogen
atom from the substrate, while the water molecule forms a
hydrogen bond with the substrate carbonyl group, possibly
lowering the p K[a] of the abstracted proton.
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