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Figure 6.
Fig. 6. Superimposition of the crystal structures of
IV703 bound to TNFRc1 (purple, this study) and that of TNF- bound to
TNFRc1 (green; ref. 11). Note that Tyr-108 (TNF- ) normally
interacts with Ala-62 (TNFRc1) (11); this receptor residue is
bound to IV703 in our structure.
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