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Figure 6.
Figure 6 Comparison of the IL-17F surface and the TrkA-binding
site on NGF. (A and B) The molecular surface of IL-17F is
oriented as in Figure 5. IL-17F is colored according to the
electrostatic surface potential: red, -5 kT; white, 0 kT; and
blue, +5 kT. The positions of the cavities are indicated by the
circles. (C) The molecular surface of NGF is shown in the same
orientation as IL-17F in (B) with the two protomers of the dimer
colored red and blue; domain 5 of TrkA is shown as a green
ribbon (Wiesmann et al., 1999).
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