Figure 6 - full size

 

Figure 6.
Figure 6 Superposed view of thyroxine on the ligand PBP at the TTR-PBP binding site. (a) In its principal binding mode PBP1, the Br atoms Br2 and Br6 occupy the outer pockets of thyroxine while (b) in the secondary binding mode PBP2, Br3 and Br5 are in the inner pockets of the hormone. I atoms are shown in gold and Br atoms are in rust red. The figures were created using the program XOBJECTS (M. E. M. Noble, unpublished program).

The above figure is reprinted by permission from the IUCr: Acta Crystallogr D Biol Crystallogr (2000, 56, 1085-1095) copyright 2000.