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Figure 5.
Figure 5. Structures of Zn2+-binding `knuckles'. (a) Stereo
view of the RPB9 Zn2+-binding region (knuckles). Structures of
the RPB9 ensemble were superimposed with respect to the
mainchain atoms of residues 13-31 and 41-55. Sulfur atoms are
shown as yellow balls, and Zn2+ as a white sphere. Predicted
amide-sulfur hydrogen bonds are shown in yellow dashed lines:
K20 NH-C18 Sg, C21 NH-C18 Sg, K48 NH-C46 Sg, and C49 NH-C46 Sg;
N23 NH-C21 Sg is not shown. The protein is otherwise depicted in
red. (b) Superposition of the Zn2+-binding region of RPB9 (red)
and TFIIS (green) aligned with respect to the mainchain atoms of
residues 13-31 and 41-55.
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