Figure 5 - full size

 

Figure 5.
Figure 5. The amino acid sequence of pNR-2/pS2 aligned with corresponding residues in the trefoil motifs of the mammalian trefoil peptides PSP, hSP and hITF. The disulphide bonds and secondary structure elements determined in this present work are shown at the top of the diagram. Residues identical with those in pNR-2/pS2 have been shaded in the diagram. A consensus sequence motif derived from the mammalian trefoil peptides is given at the bottom of the diagram. The sequences of porcine, human, rat and mouse spasmolytic polypeptide, human and rat intestinal trefoil factor, and human and mouse pS2 were used to produce the consensus.

The above figure is reprinted by permission from Elsevier: J Mol Biol (1997, 267, 418-432) copyright 1997.