|
Figure 5.
ATP-binding mode of N-MNK. A, the structure of ATP-bound
N-MNK showing the side chains of hydrophobic amino acids in blue
and of Glu^1081 in yellow, which are in contact with the ATP
molecule. The unstructured loop was omitted for simplicity. In
the zoom on the ATP-binding cavity, the amino acids are labeled.
B, overlay of the structures of ATP-free (pink) and ATP-bound
(red) N-MNK, highlighting the regions of structural variation.
|
