Figure 5.
Figure 5. Hydration Patterns in the Active-Site Pocket Near
the ThDP Cofactor The substitution of the bulky isoleucine
by alanine in the I206Aα mutant changes the hydration pattern
around the cofactor. The wild-type structure (green) is
overlayed with the mutant in complex with 3-deazaThDP (cyan).
The above figure is reprinted
from an Open Access publication published by Cell Press:
Structure
(2008,
16,
1860-1872)
copyright 2008.
