Figure 5 - full size

 

Figure 5.
N-cap configurations of the EphA1tm helix depending on the ionization state of Glu^547 carboxyl group. Possible transient hydrogen bond connections in the N terminus of the TM helix observed during MD relaxation of the NMR-derived structures of the EphA1tm dimer embedded in the DMPC/DHPC bicelles at pH 4.3 (A) and 6.3 (B) are shown by dashed lines.

The above figure is reprinted from an Open Access publication published by the ASBMB: J Biol Chem (2008, 283, 29385-29395) copyright 2008.