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Figure 5.
Fig. 5. Comparison of shared and distinct contact surfaces in
the IL-23 and IL-12 complexes. (a) Histogram of buried surface
area contributed by each p40 residue involved in p19 and/or p35
interaction. (b) Surface representation of p40 (middle panel),
with residues interacting with p19 (pink), p35 (green), or p19
and p35 (yellow) highlighted. The p40-interacting surfaces of
p19 (left panel in pink) and p35 (right panel in green) are
shown with a transparent p40 overlay to demonstrate orientation.
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