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Figure 5.
Figure 5. Glu73 of G2/Switch I Senses the Nucleotide Loading
State in Dimeric psToc34
(A) psGlu73 is solvent exposed in
psToc34 in the GMPPNP-bound state. A water that might be in
position for nucleophilic attack on the γ-phosphate is shown as
a small blue sphere. The water is in hydrogen-bonding distance
to Gly74 of the G2 region.
(B) In the GDP-bound state (PDB
code: 1H65) (Sun et al., 2002), psGlu73 is turned toward the
nucleotide and takes the position of the γ-phosphate. It then
coordinates the Mg^2+ ion.
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