Figure 5 - full size

 

Figure 5.
Figure 5. ADP- and AMPPNP-Bound GRP94 Have Identical Conformations
(A) Overlay of the two nucleotide-bound complexes. The AMPPNP complex is in blue, and the ADP complex is in cyan. Only one protomer of the GRP94 dimer is shown.
(B) Stereo view of the bound AMPPNP. SA omit electron density contoured at 1.3 σ is shown with a 2 Å carve radius. The density for the nucleotide is shown in green, for the residues of the N domain in pink, and for the M domain in blue. The position of Arg448 is indicated, and the distance to the γ-phosphate of the AMPPNP is shown with a dashed line.

The above figure is reprinted from an Open Access publication published by Cell Press: Mol Cell (2007, 28, 41-56) copyright 2007.