Figure 5.
FIGURE 5. Close up on the active sites of native MutB (A),
E254Q·sucrose (B), MutB·castanospermine (C),
MutB·deoxynojirimycin (D), and D200A·glucose (E).
Electron density 2F[o] - F[c] maps are contoured at 1 .
Catalytic residues are highlighted in green, and other active
site residues are in yellow. The aromatic clamp in magenta
corresponds to conformation 1, and that in cyan corresponds to
conformation 2.
The above figure is reprinted
by permission from the ASBMB:
J Biol Chem
(2007,
282,
28126-28136)
copyright 2007.
.
Catalytic residues are highlighted in green, and other active
site residues are in yellow. The aromatic clamp in magenta
corresponds to conformation 1, and that in cyan corresponds to
conformation 2.