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Figure 5.
Figure 5 Molecular model of an initial step in the SV40 DNA
replication. The PEN-4 structure is shown in black, two
hexameric helicase domains are in blue (PDB Id: 1N25), modeled
DNA is shown as a stick model and colored per atom type (carbon
in yellow, oxygen in red, nitrogen in blue, and phosphorus in
purple). Position of the initially melted 8 nt fragment of EP
with respect to the PEN box is highlighted with a yellow
rectangle. Relative positions of the C-terminus in the OBD (aa
253) and N-terminus in the helicase domain (aa 266) are
indicated. See text for more detail.
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