Figure 5 - full size

 

Figure 5.
FIGURE 5. Comparison of the SH3I/Cbl-b interface from CIN85A and CMSA. Electrostatic potential surfaces of SH3 domains from CIN85A/Cbl-b (left) and CMSA/Cbl-b (right) complexes that bind the peptide in a class I-like orientation are shown. The Cbl-b peptides are represented in sticks, and their residues are indicated. n-Src loops are labeled in both structures, and binding pockets are indicated with arrows.

The above figure is reprinted by permission from the ASBMB: J Biol Chem (2006, 281, 38845-38853) copyright 2006.