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Figure 5.
Figure 5: ABC exporter schematics.
Figure 5 : ABC
exporter schematics. Unfortunately we are unable to
provide accessible alternative text for this. If you
require assistance to access this image, or to obtain a
text description, please contact npg@nature.com-
a, Earlier cartoons depict two compact transporter halves
(subunits) arranged side-by-side, suggesting separation during
the transport cycle. The grey box indicates the location of the
membrane. b, Schematic of Sav1866 in the observed,
outward-facing conformation. The cartoon emphasizes the domain
swapping and subunit twisting. Arrows indicate the release of
bound drug into the extracellular space.
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