Figure 5 - full size

 

Figure 5.
FIGURE 5. Comparison of the active site of AzoR with that of NQO1. One active site is shown for each of AzoR (a) and rat NQO1 (b) (Protein Data Bank accession code 1QRD). The flavin cofactors, duroquinone, and the side chains of conserved amino acid residues in both enzymes are represented by a stick model, with carbon atoms in gray, oxygen atoms in red, nitrogen atoms in blue, and phosphorous atoms in orange. The polypeptide moieties of one subunit for each enzyme are drawn as C traces in yellow and green.

The above figure is reprinted by permission from the ASBMB: J Biol Chem (2006, 281, 20567-20576) copyright 2006.