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Figure 5.
Figure 5. Membrane interaction model of the
Cdc42-collybistin II complex. (a) The electrostatic potential of
the open conformation of the Cdc42-collybistin II complex,
calculated at zero ionic strength and contoured at 1.5 kT (blue)
and -1.5 kT (red). (b) Model of the interaction between the
plasma membrane and the complex in the open conformation. The
observed conformation of the Cdc42 C terminus is colored in
cyan, whereas the physiologically relevant conformations present
in the Cdc42-Dbs and Cdc42-GDI complexes are colored in gray and
red, respectively.
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