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Figure 5.
Figure 5. Comparison of the Vts1p-SAM–SRE complex with the
structures of other SAM domain–containing proteins. (a)
Crystal structure of the RuvA SAM-like domain in complex DNA^45
(PDB entry 1C7Y); red and yellow helices correspond to those in
Vts1p-SAM shown in d. (b) Crystal structure of the heterodimer
formed by the Yan and Mae SAM domains^17 (1SV0), colored light
and dark gray, respectively. (c) Crystal structure of the
homodimer formed by the EphB2 SAM domain^18 (1B4F). (d) Overlay
of the Vts1p-SAM–SRE complex (blue, red and yellow) and the
crystal structure of Smaug (light green; 1OXJ) solved in its
free state^7.
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