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Figure 5.
Figure 5. Covalent binding of the 4-(2-aminoethyl)-benzene
sulphonyl fluoride inhibitor (AEBSF, ball-and-stick
representation: green, carbon; red, oxygen; and blue, nitrogen)
towards the active site of DPIV. The Figures was were prepared
using the program PYMOL (http://pymol.sourceforge.net/). (a)
Surface representation of the DPIV residues around the active
site. (b) Ball-and-stick representation of the DPIV residues (in
light blue) and around the active site (beige). Intermolecular
hydrogen bonds are given as broken black lines, the 2F[obs]
-F[calc] electron density omit map (blue mesh, contoured at 1s)
is given for the inhibitor and the Tyr547 phenolic group of DPIV.
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