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Figure 5.
Figure 5. DntR–ligand interactions. Stereoviews showing
substrate–protein interactions for the acetate-bound crystals
(a) and for the models of DntR containing salicylate (b) and
2,4-DNT (c) in the inducer-binding cavities. The surface defined
by protein residues is shown in light purple. Both side-chain
and main-chain atoms of amino acid residues that line the
inducer-binding cavity are shown in ball-and-stick
representation with carbon atoms coloured grey, oxygen atoms red
and nitrogen atoms blue. Acetate, salicylate and 2,4-DNT are
also shown in ball-and-stick mode with carbon atoms coloured
yellow, oxygen atoms red and nitrogen atoms blue. Water
molecules are shown as red spheres. Direct and water-mediated
hydrogen bonding interactions are shown as green and yellow
broken lines, respectively.
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