Figure 5 - full size

Figure 5. FIG. 5. Close up stereoview of the Site 1 drug-binding site of pentamidine. Interaction distances are given in angstrom. Hydrogen bonds are depicted by red dashed lines, van der Waals contacts are depicted by a black dashed line, a -cation interaction is depicted by a green dashed line, and stacking interactions (closest contact) are depicted by purple dashed lines. Note that no negatively charged side chains are found within 6 Å of either of the amidinic nitrogens.

The above figure is reprinted by permission from the ASBMB: J Biol Chem (2004, 279, 14365-14371) copyright 2004.