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Figure 5.
Fig 5. Determination of the specificity conferring code of
ca-activating domains. The primary sequence between core A4 and
A5 (see Fig. 3) of nine ca activating domains are aligned by
using the Clustal method. Based on the structural data of DhbE,
extraction of the 10 residues conferring the substrate
specificity leads to the identification of the signature
sequence of ca activating A domain. The asterisks define the
residues that allow discrimination between DHB and SAL.
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